Metaphysics and epistemology form the foundation of philosophical inquiry. These fields grapple with fundamental questions about reality, existence, and the nature of knowledge. From ancient Greek thinkers to modern philosophers, debates in these areas have shaped our understanding of the world. Key concepts include ontology, a priori and a posteriori knowledge, causation, and determinism. Major theories like substance dualism, materialism, and idealism offer competing views on the nature of reality. Epistemological approaches such as foundationalism and coherentism explore how we justify our beliefs and acquire knowledge.