🥼organic chemistry review

Schiff bases

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Schiff bases are compounds formed by the nucleophilic addition of primary amines to carbonyl compounds (aldehydes or ketones) followed by the removal of water (dehydration), resulting in a C=N double bond. These products are named after Hugo Schiff, who first described their formation.

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