🥼organic chemistry review

Dieckmann cyclization

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Dieckmann cyclization is a chemical reaction where a diester undergoes intramolecular condensation in the presence of a base, resulting in the formation of a cyclic β-keto ester. It's a specific type of intramolecular Claisen condensation that is useful for synthesizing five or six-membered rings.

AP course connection

Topic 23.9: 23.9 Intramolecular Claisen Condensations: The Dieckmann Cyclization

Unit 23
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