Spleen

Definition

The spleen is an organ located in the upper left abdomen that filters blood, removes old red blood cells, and plays a critical role in immune response by producing white blood cells.

5 Must Know Facts For Your Next Test

1. The spleen contains white pulp, which is rich in lymphocytes including T and B cells essential for adaptive immunity.
2. Red pulp in the spleen is responsible for filtering out old or damaged red blood cells and pathogens from the bloodstream.
3. The spleen acts as a reservoir for blood and can release it during hemorrhagic shock or other emergencies.
4. Splenic macrophages engulf and destroy infectious agents, contributing to both innate and adaptive immune responses.
5. Despite its functions, a person can live without a spleen; however, they may be more susceptible to infections.

Related terms

Lymphocytes:

White blood cells involved in the adaptive immune response.

Macrophages:

Immune cells that engulf and digest pathogens and cellular debris.

Hemorrhagic Shock: A condition of reduced tissue perfusion due to severe loss of blood.