Sofosbuvir

Definition

Sofosbuvir is an antiviral medication used primarily to treat hepatitis C virus (HCV) infections. It functions as a nucleotide analog inhibitor of the HCV RNA polymerase.

5 Must Know Facts For Your Next Test

1. Sofosbuvir inhibits the RNA-dependent RNA polymerase, which is essential for viral replication.
2. It is often used in combination with other antiviral drugs for increased efficacy.
3. Sofosbuvir has a high barrier to resistance compared to other HCV medications.
4. Common side effects include fatigue, headache, and nausea.
5. It was approved by the FDA in 2013 for the treatment of chronic hepatitis C.

Related terms

Hepatitis C Virus (HCV): A viral infection that causes liver inflammation and can lead to serious liver damage.

RNA-dependent RNA Polymerase: An enzyme that catalyzes the replication of RNA from an RNA template, crucial for the replication of RNA viruses like HCV.

Antiviral Medication: Drugs designed to treat viral infections by inhibiting the development and spread of viruses within the host body.