RhoGAM

Definition

RhoGAM is an injectable medication containing Rh immunoglobulin (Ig) used to prevent Rh incompatibility in pregnancies. It helps protect Rh-negative mothers from developing antibodies against Rh-positive fetal blood cells.

5 Must Know Facts For Your Next Test

1. RhoGAM is administered to Rh-negative mothers during and after pregnancy to prevent hemolytic disease of the newborn (HDN).
2. The medication works by neutralizing any Rh-positive fetal blood cells that enter the mother's bloodstream.
3. RhoGAM is typically given at around 28 weeks of pregnancy and within 72 hours after childbirth.
4. It prevents the mother's immune system from mounting an immune response against future Rh-positive pregnancies.
5. Without RhoGAM, an Rh-negative mother can develop anti-Rh antibodies, leading to complications in subsequent pregnancies.

Related terms

Hemolytic Disease of the Newborn (HDN): A serious condition where maternal antibodies attack fetal red blood cells.

Rh Incompatibility: A condition where an Rh-negative mother carries an Rh-positive fetus, risking maternal antibody production against fetal cells.

Rh Factor:

An antigen present on red blood cells; its presence or absence determines whether a person's blood type is positive or negative.