Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025
Definition
Psoriatic arthritis is a chronic autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (arthritis). It results from an aberrant immune response attacking healthy tissue.
Psoriatic arthritis often develops in individuals who already have psoriasis, a skin condition marked by red, scaly patches.
The exact cause of psoriatic arthritis is unknown, but genetic, environmental, and immunological factors are believed to play a role.
Common symptoms include joint pain, stiffness, swelling, and reduced range of motion.
Diagnosis typically involves clinical evaluation, imaging studies such as X-rays or MRIs, and laboratory tests including inflammatory markers like ESR and CRP.
Treatment may include nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologic agents targeting specific immune pathways.
Related terms
Autoimmune Disease: A condition in which the immune system mistakenly attacks the body's own tissues.
Psoriasis: A chronic skin condition characterized by red, scaly patches due to rapid skin cell production.