Polyomaviridae

Definition

Polyomaviridae is a family of small, non-enveloped DNA viruses known to infect mammals and birds. Some members of this family can cause skin and eye infections in humans.

5 Must Know Facts For Your Next Test

1. Polyomaviridae viruses have a circular double-stranded DNA genome.
2. Human polyomaviruses include BK virus (BKV) and JC virus (JCV), which can become pathogenic in immunocompromised individuals.
3. Merkel cell polyomavirus (MCV) is associated with Merkel cell carcinoma, a rare but aggressive skin cancer.
4. Polyomaviruses are typically transmitted through respiratory droplets or contact with contaminated surfaces.
5. Infections are often asymptomatic but can lead to severe complications in people with weakened immune systems.

Related terms

BK Virus (BKV): A human polyomavirus that can cause kidney disease in transplant patients.

JC Virus (JCV): A human polyomavirus that can lead to progressive multifocal leukoencephalopathy (PML) in immunocompromised individuals.

Merkel Cell Carcinoma: An aggressive form of skin cancer associated with Merkel cell polyomavirus infection.