🦠microbiology review

Murein

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Murein, also known as peptidoglycan, is a polymer that forms a protective layer outside the plasma membrane of most bacteria. It provides structural strength and shape to the cell.

5 Must Know Facts For Your Next Test

  1. Murein is composed of sugar chains cross-linked by short peptides.
  2. It is essential for maintaining cell shape and preventing osmotic lysis in bacterial cells.
  3. The structure of murein varies between Gram-positive and Gram-negative bacteria.
  4. Enzymes like lysozyme can break down murein, leading to cell lysis.
  5. Antibiotics such as penicillin target the synthesis of murein, inhibiting bacterial growth.
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