🦠microbiology review

Miliary tuberculosis

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Miliary tuberculosis is a form of tuberculosis characterized by a wide dissemination into the human body and tiny nodules resembling millet seeds in the affected organs. It can affect multiple organ systems and is often diagnosed through imaging and laboratory tests.

Course connection

Topic 22.2: 22.2 Bacterial Infections of the Respiratory Tract

Unit 22

5 Must Know Facts For Your Next Test

  1. It is caused by Mycobacterium tuberculosis spreading through the bloodstream.
  2. Miliary tuberculosis often presents with symptoms like fever, weight loss, and night sweats.
  3. The disease can affect organs beyond the lungs, including the liver, spleen, and bone marrow.
  4. Chest X-rays or CT scans typically show a 'miliary' pattern of numerous small nodules throughout the lungs.
  5. Tuberculin skin tests may be negative due to an overwhelming infection causing immunosuppression.