🦠microbiology review

Lockjaw

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Lockjaw, also known as trismus, is a condition characterized by the inability to open the mouth fully due to muscle spasms in the jaw. It is often associated with tetanus infection caused by Clostridium tetani.

5 Must Know Facts For Your Next Test

  1. Lockjaw is commonly caused by the neurotoxin produced by Clostridium tetani.
  2. The condition can lead to severe complications, including difficulty swallowing and breathing.
  3. Early symptoms of lockjaw include stiffness around the jaw and neck muscles.
  4. Vaccination with the tetanus toxoid vaccine is effective in preventing lockjaw.
  5. Treatment involves antitoxins, antibiotics, and supportive care such as muscle relaxants.
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