🦠microbiology review

Influenza C virus

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Influenza C virus is a type of influenza virus that primarily infects humans and swine. It generally causes mild respiratory illness and is less common than Influenza A and B viruses.

5 Must Know Facts For Your Next Test

  1. Influenza C virus has a single-stranded RNA genome.
  2. It is less likely to cause epidemics compared to Influenza A and B.
  3. Humans of all ages can be infected, but it often affects children more severely.
  4. The virus lacks the neuraminidase (NA) protein found in Influenza A and B, instead having a hemagglutinin-esterase-fusion (HEF) protein.
  5. Reinfection with Influenza C can occur throughout life due to limited immunity.
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