🦠microbiology review

Ergotism

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Ergotism is a condition caused by consuming grains contaminated with ergot fungi, primarily Claviceps purpurea. It leads to severe symptoms including convulsions, hallucinations, and gangrene due to vasoconstrictive alkaloids produced by the fungus.

5 Must Know Facts For Your Next Test

  1. Ergotism results from the ingestion of toxic alkaloids produced by the ergot fungus.
  2. Symptoms of ergotism include muscle spasms, fever, hallucinations, and gangrene.
  3. Historically known as 'St. Anthony's Fire,' it has caused numerous epidemics throughout history.
  4. The primary species responsible for ergotism in humans is Claviceps purpurea.
  5. Ergot alkaloids are potent vasoconstrictors affecting blood flow and leading to tissue damage.
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