Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025
Definition
Enterobacter spp. are a group of Gram-negative, facultatively anaerobic bacteria commonly found in the intestinal tract of humans and animals. They are known for causing opportunistic infections and demonstrating significant drug resistance.
Enterobacter spp. often exhibit resistance to multiple antibiotics due to the presence of extended-spectrum beta-lactamases (ESBLs).
These bacteria can cause various infections including urinary tract infections, respiratory infections, and bacteremia.
Carbapenem-resistant Enterobacteriaceae (CRE) includes strains of Enterobacter that are resistant to carbapenem antibiotics, posing significant treatment challenges.
The genetic mechanisms behind their drug resistance include plasmid-mediated transfer of resistance genes.
Infection control measures such as hand hygiene and isolation protocols are critical in preventing the spread of these antibiotic-resistant bacteria.
Related terms
Extended-Spectrum Beta-Lactamases (ESBLs): Enzymes produced by some bacteria that can break down a wide variety of beta-lactam antibiotics.
Carbapenem-Resistant Enterobacteriaceae (CRE): A family of bacteria that are resistant to carbapenem antibiotics, including certain strains of Enterobacter.
Plasmid-Mediated Resistance: A form of antibiotic resistance where genes responsible for drug resistance are carried on plasmids which can be transferred between bacteria.