🦠microbiology review

Atopobium vaginae

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Atopobium vaginae is a Gram-positive anaerobic bacterium associated with bacterial vaginosis, an imbalance of the vaginal microbiota. It is often identified through molecular techniques like PCR due to its role in urogenital infections.

5 Must Know Facts For Your Next Test

  1. Atopobium vaginae is frequently detected in women with bacterial vaginosis but is not typically found in healthy vaginal flora.
  2. It produces lactic acid, which can contribute to the acidic environment of the vagina.
  3. Molecular techniques such as PCR and sequencing are commonly used for its identification due to its difficulty to culture.
  4. The presence of Atopobium vaginae in the vaginal microbiota can be an indicator of dysbiosis and potential risk for preterm birth or pelvic inflammatory disease.
  5. Treatment for bacterial vaginosis involving Atopobium vaginae may include antibiotics like metronidazole or clindamycin.
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