Antigenic

Definition

Describes substances that can provoke an immune response in the body by interacting with specific antibodies or T-cell receptors. These substances are typically foreign molecules such as pathogens, toxins, or other foreign particles.

5 Must Know Facts For Your Next Test

1. Antigenic substances are recognized by the immune system and elicit a response aimed at neutralizing or eliminating them.
2. The antigenic determinant, also known as an epitope, is the specific part of an antigen that is recognized by antibodies or T-cell receptors.
3. Antigenic variation allows pathogens to evade the host’s immune system by altering their surface proteins.
4. Vaccines rely on antigenic properties to stimulate an immune response without causing disease.
5. Autoantigens are normal body components that are mistakenly targeted by the immune system in autoimmune diseases.

Related terms

Epitope:

The specific part of an antigen molecule to which an antibody attaches itself.

Antibody:

A protein produced by B cells in response to an antigen; binds specifically to that antigen.

Autoantigen: A normal protein or complex of proteins that is recognized by the immune system of patients with certain autoimmune diseases.