Multiple integrals extend single-variable integration to functions of two or more variables. They allow us to calculate volumes, surface areas, and other quantities in higher dimensions, making them essential for solving problems in physics, engineering, and economics. The process involves integrating a function over a region in two or three dimensions. Key concepts include double and triple integrals, iterated integrals, Fubini's Theorem, and change of variables. Understanding the geometric interpretation is crucial for setting up and solving problems.