A non-inertial frame is a reference frame that is accelerating or rotating, causing observers within it to experience fictitious forces, such as centrifugal force or Coriolis force. These frames are essential for understanding the effects of acceleration and rotation in physical systems, leading to important implications in relativity and the addition of velocities. In non-inertial frames, the laws of motion appear altered, which is critical when analyzing the behavior of objects in such conditions.