The position-momentum commutation relation is a fundamental concept in quantum mechanics that expresses the non-commutativity of the position operator $$\hat{x}$$ and the momentum operator $$\hat{p}$$. It is mathematically represented as $$[\hat{x}, \hat{p}] = \hat{x}\hat{p} - \hat{p}\hat{x} = i\hbar$$, where $$i$$ is the imaginary unit and $$\hbar$$ is the reduced Planck's constant. This relation highlights that the precise measurement of position and momentum cannot occur simultaneously, revealing the inherent limitations of measurement in quantum systems.