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RDA for Vitamin B12

Written by the Fiveable Content Team โ€ข Last updated September 2025
Written by the Fiveable Content Team โ€ข Last updated September 2025

Definition

The Recommended Dietary Allowance (RDA) for Vitamin B12 is the average daily intake level that is sufficient to meet the nutrient requirements of most healthy individuals. This measure helps ensure adequate intake of this essential nutrient, which plays a crucial role in nerve function, red blood cell formation, and DNA synthesis.

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5 Must Know Facts For Your Next Test

  1. The RDA for Vitamin B12 varies by age and life stage, with adults typically requiring about 2.4 micrograms per day.
  2. Vitamin B12 is primarily found in animal-based foods such as meat, fish, eggs, and dairy products, making it important for vegetarians and vegans to seek alternative sources or supplements.
  3. Deficiency in Vitamin B12 can lead to neurological issues and megaloblastic anemia, which is characterized by the production of large and immature red blood cells.
  4. Certain groups, such as older adults, individuals with gastrointestinal disorders, and those who have had gastric surgery, may have higher requirements or impaired absorption of Vitamin B12.
  5. Dietary Reference Intakes (DRIs) consider both RDA and Adequate Intake (AI) levels for specific populations to ensure optimal health outcomes.

Review Questions

  • What are the implications of not meeting the RDA for Vitamin B12 in different populations?
    • Failing to meet the RDA for Vitamin B12 can lead to serious health issues, particularly in populations at higher risk like older adults and vegetarians. Insufficient intake may result in megaloblastic anemia, neurological impairments, and cognitive decline. Monitoring intake levels is crucial for these groups to prevent deficiencies and associated health problems.
  • How does intrinsic factor influence Vitamin B12 absorption, and what happens if it is deficient?
    • Intrinsic Factor is essential for the absorption of Vitamin B12 in the intestines. If there is a deficiency of intrinsic factor, often due to autoimmune conditions like pernicious anemia, it can lead to poor absorption of Vitamin B12 despite adequate dietary intake. This deficiency can cause severe health consequences, including anemia and neurological damage.
  • Evaluate the role of dietary sources versus supplements in achieving adequate levels of Vitamin B12 to meet the RDA.
    • Dietary sources of Vitamin B12 are crucial for most individuals; however, some populations may struggle to meet their RDA through food alone due to dietary restrictions or absorption issues. Supplements can play a significant role in preventing deficiency, especially for vegetarians, vegans, and those with gastrointestinal disorders. Balancing both dietary sources and supplements ensures that individuals achieve optimal Vitamin B12 levels while supporting overall health.

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