🥼organic chemistry review

Silyl ether

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Silyl ethers are compounds formed by the reaction of alcohols with silyl chlorides, effectively protecting the alcohol group by replacing the hydrogen atom bonded to oxygen with a silyl group. This protection method is widely used in organic synthesis to prevent undesirable reactions at the alcohol site during subsequent chemical reactions.