🥼organic chemistry review

Semiconservative replication

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Semiconservative replication is the method by which DNA duplicates itself before cell division, ensuring each new cell receives an exact copy of the DNA. In this process, each original strand serves as a template for a new complementary strand, resulting in two DNA molecules that each contain one original and one newly synthesized strand.

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