Koenigs–Knorr reaction

Definition

The Koenigs–Knorr reaction is a glycosylation process used in organic chemistry for the synthesis of glycosides from halogenated sugars and alcohols, typically using a silver salt catalyst. It is particularly significant in the modification of carbohydrates to form various glycosidic linkages.

Related terms

Glycosides: Glycosides are compounds formed from a sugar and another functional group via a glycosidic bond, functioning as crucial components in many biological processes.

Glycosylation:

This is the enzymatic process that attaches glycans (sugars) to proteins, lipids, or other organic molecules, playing critical roles in molecular recognition and signal transduction in cells.

Halogenated sugars: These are sugar molecules where one or more hydrogen atoms have been replaced by a halogen atom (such as chlorine or bromine), often used as reactive intermediates in chemical syntheses