🥼organic chemistry review

Conjugate addition

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Conjugate addition is a type of nucleophilic addition reaction where a nucleophile adds to the β-carbon of an α,β-unsaturated aldehyde or ketone. This process expands the molecule by forming a new carbon-carbon bond, effectively incorporating the nucleophile into the molecule.