🥼organic chemistry review

Alkoxide ion, RO–

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

An alkoxide ion is the conjugate base of an alcohol, formed by the deprotonation of the hydroxyl group (OH) in an alcohol molecule, resulting in a negatively charged oxygen atom bonded to an alkyl group (R). It plays a crucial role in various organic reactions, especially as a strong nucleophile.