Weil’s disease

Definition

Weil's disease is a severe form of leptospirosis caused by the bacterium Leptospira interrogans. It primarily affects the kidneys and liver, leading to serious complications.

5 Must Know Facts For Your Next Test

1. Weil's disease is often transmitted through contact with water contaminated by the urine of infected animals.
2. Symptoms include jaundice, kidney failure, and bleeding tendencies.
3. The bacteria can enter the human body through cuts or abrasions on the skin or through mucous membranes.
4. Diagnosis is typically confirmed via serological tests such as the microscopic agglutination test (MAT).
5. Treatment usually involves antibiotics like doxycycline or penicillin.

Review Questions

• What are the primary organs affected by Weil’s disease?
• How is Weil’s disease commonly transmitted?
• Which diagnostic test is used to confirm a case of Weil’s disease?

Related terms

Leptospira interrogans: A spirochete bacterium responsible for leptospirosis, including Weil's disease.

Jaundice: A yellowing of the skin and eyes due to elevated levels of bilirubin, often seen in Weil's disease.

Microscopic Agglutination Test (MAT): A serological test used to detect antibodies against Leptospira species.