Warthin-Starry silver-precipitate procedure

Definition

The Warthin-Starry silver-precipitate procedure is a histological staining method used to detect certain bacteria in tissue samples, particularly those responsible for respiratory infections. It utilizes silver nitrate to stain the organisms, making them visible under a microscope.

5 Must Know Facts For Your Next Test

1. The Warthin-Starry stain is particularly useful in identifying Helicobacter pylori and Bartonella henselae.
2. It is a silver-based staining technique that highlights bacteria as black or dark brown against a pale yellow background.
3. This procedure is often employed when other staining methods fail to clearly identify the presence of certain bacteria.
4. The Warthin-Starry stain can be used on both tissue biopsies and cytological preparations.
5. It requires careful handling and precise timing during the staining process to avoid artifacts.

Review Questions

Related terms

Gram Stain:

A common bacterial staining technique that differentiates bacteria into Gram-positive and Gram-negative based on cell wall composition.

Acid-Fast Stain:

A differential stain used primarily to identify Mycobacterium species by their resistance to decolorization by acids.

Histology: The study of the microscopic structure of tissues.