🦠microbiology review

Tuberculoid (paucibacillary) Hansen’s disease

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Tuberculoid (paucibacillary) Hansen’s disease is a form of leprosy characterized by a limited number of skin lesions and peripheral nerve involvement. It is less severe than lepromatous leprosy and has fewer bacteria present in the lesions.

5 Must Know Facts For Your Next Test

  1. Tuberculoid Hansen’s disease involves well-defined, hypoesthetic skin lesions with loss of sensation.
  2. It primarily affects the peripheral nerves, leading to muscle weakness and atrophy.
  3. The immune response in tuberculoid Hansen's disease is strong, resulting in fewer bacteria compared to other forms.
  4. Diagnosis typically involves clinical examination, skin smears, and sometimes biopsy showing granulomas.
  5. Treatment includes multidrug therapy (MDT) usually involving dapsone and rifampicin for six months.

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