TSH-receptor antibodies are autoantibodies that target the thyroid-stimulating hormone receptor, often leading to hyperthyroidism. They play a key role in autoimmune thyroid diseases such as Graves' disease.
5 Must Know Facts For Your Next Test
TSH-receptor antibodies stimulate the thyroid gland to produce excessive thyroid hormones, causing hyperthyroidism.
These antibodies are primarily associated with Graves' disease, an autoimmune disorder.
The presence of TSH-receptor antibodies is used as a diagnostic marker for Graves' disease.
TSH-receptor antibodies can cross the placenta and affect fetal thyroid function during pregnancy.
Management of Graves' disease may involve anti-thyroid medications, radioactive iodine therapy, or surgery.
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Related terms
Graves' Disease: An autoimmune disorder where TSH-receptor antibodies cause hyperthyroidism.
Hyperthyroidism: A condition where the thyroid gland produces excess thyroid hormones.
Autoantibody: An antibody produced by the immune system that mistakenly targets and attacks the body's own tissues.