๐Ÿฆ microbiology review

key term - Thyroid-stimulating immunoglobulin (TSI)

Definition

Thyroid-stimulating immunoglobulin (TSI) is an antibody that mimics thyroid-stimulating hormone (TSH), leading to overstimulation of the thyroid gland. It is commonly associated with Graves' disease, an autoimmune disorder.

5 Must Know Facts For Your Next Test

  1. TSI is responsible for the hyperthyroidism seen in Graves' disease.
  2. It binds to TSH receptors on the thyroid gland, causing excess production of thyroid hormones.
  3. Elevated levels of TSI can be detected through specific blood tests.
  4. Patients with high TSI levels often present symptoms such as weight loss, rapid heartbeat, and bulging eyes.
  5. Management of conditions involving TSI typically includes antithyroid medications or treatments aimed at reducing thyroid activity.

Review Questions

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