🦠microbiology review

Thermal death time (TDT)

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Thermal Death Time (TDT) is the shortest time required to kill all microorganisms in a liquid suspension at a specific temperature. It is a critical parameter in sterilization processes.

5 Must Know Facts For Your Next Test

  1. TDT varies depending on the type of microorganism and the medium in which it is found.
  2. Higher temperatures generally result in shorter TDTs.
  3. TDT is an important factor in designing pasteurization and sterilization protocols.
  4. Microorganisms with spores typically have longer TDTs compared to non-spore forming bacteria.
  5. TDT can be influenced by environmental factors such as pH and moisture content.
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