🦠microbiology review

Streptomyces

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Streptomyces is a genus of Gram-positive bacteria known for its complex life cycle and production of medically important antibiotics. It is characterized by its filamentous structure and soil-dwelling nature.

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5 Must Know Facts For Your Next Test

  1. Streptomyces is responsible for producing over two-thirds of the clinically useful antibiotics of natural origin, including streptomycin and tetracycline.
  2. These bacteria have a high GC content in their DNA, which contributes to their ability to produce secondary metabolites.
  3. Streptomyces species undergo a distinct life cycle that includes spore formation, germination, vegetative growth, and sporulation.
  4. They are commonly found in soil and decaying vegetation where they play a crucial role in organic matter decomposition and nutrient cycling.
  5. Genetic engineering techniques have been employed to enhance antibiotic production in Streptomyces, making it a key organism in pharmaceutical biotechnology.

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