Streptococcus pyogenes

Definition

Streptococcus pyogenes is a Gram-positive bacterium responsible for various infections in humans. It is known for causing diseases such as strep throat, scarlet fever, and rheumatic fever.

5 Must Know Facts For Your Next Test

1. Streptococcus pyogenes produces virulence factors like streptolysins and streptokinase that aid in infection.
2. It is beta-hemolytic, meaning it completely lyses red blood cells on blood agar plates.
3. The bacterium can be identified using fluorescent antibody techniques targeting the M protein on its surface.
4. Infections by Streptococcus pyogenes can lead to serious complications such as acute glomerulonephritis and necrotizing fasciitis.
5. Penicillin remains one of the most effective treatments against Streptococcus pyogenes infections.

Review Questions

• What type of hemolysis does Streptococcus pyogenes exhibit on blood agar plates?
• Name two virulence factors produced by Streptococcus pyogenes.
• Which antibody technique is used to identify Streptococcus pyogenes in the laboratory?

Related terms

Beta-hemolysis: A type of hemolysis where bacteria completely lyse red blood cells, creating a clear zone around colonies on blood agar.

M protein:

A surface protein found on Streptococcus pyogenes that contributes to its virulence and immune evasion.

Necrotizing fasciitis: A severe soft tissue infection often caused by Streptococcus pyogenes, characterized by rapid tissue death.