🦠microbiology review

Streptococcal toxic shock-like syndrome (STSS)

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Streptococcal toxic shock-like syndrome (STSS) is a severe illness caused by Group A Streptococcus bacteria releasing toxins into the bloodstream. It leads to rapid onset of fever, low blood pressure, and multi-organ failure.

5 Must Know Facts For Your Next Test

  1. STSS is often caused by invasive strains of Group A Streptococcus.
  2. Common symptoms include high fever, hypotension, rash, and signs of organ dysfunction.
  3. Rapid diagnosis and treatment with antibiotics and supportive care are crucial for patient survival.
  4. The condition can lead to complications like acute respiratory distress syndrome (ARDS) and renal failure.
  5. Patients with pre-existing skin infections or wounds are at higher risk for developing STSS.

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