Staphylococcal scalded skin syndrome (SSSS)

Definition

Staphylococcal scalded skin syndrome (SSSS) is a severe skin infection caused by Staphylococcus aureus, characterized by widespread redness, blisters, and peeling skin. It primarily affects infants and young children.

5 Must Know Facts For Your Next Test

1. SSSS is caused by exfoliative toxins produced by Staphylococcus aureus.
2. The condition often presents with fever, irritability, and widespread erythema before progressing to blistering and desquamation.
3. Diagnosis of SSSS is primarily clinical but can be confirmed with bacterial cultures from the primary infection site.
4. Treatment typically involves hospitalization, intravenous antibiotics, and supportive care for skin healing.
5. The Nikolsky sign is positive in SSSS, indicating epidermal detachment upon gentle pressure.

Review Questions

Related terms

Staphylococcus aureus:

A gram-positive bacterium that can cause a range of infections including SSSS.

Exfoliative Toxin: Toxins produced by Staphylococcus aureus that lead to the characteristic symptoms of SSSS.

Nikolsky Sign: A clinical dermatological sign where slight rubbing of the skin results in exfoliation of its outermost layer.