A spliceosome is a complex molecular machine in the cell that removes introns from a transcribed pre-mRNA. It performs RNA splicing to produce mature mRNA molecules ready for translation.
5 Must Know Facts For Your Next Test
Spliceosomes are composed of small nuclear RNAs (snRNAs) and protein complexes.
The core snRNAs involved in the spliceosome include U1, U2, U4, U5, and U6.
Spliceosomes recognize specific sequences at the intron-exon boundaries called splice sites.
Alternative splicing by spliceosomes allows for the generation of multiple protein variants from a single gene.
Mutations affecting spliceosome components can lead to various genetic diseases and cancers.