Seroconversion

Definition

Seroconversion is the period during which a specific antibody develops and becomes detectable in the blood. It indicates a change from seronegative (absence of antibodies) to seropositive (presence of antibodies).

5 Must Know Facts For Your Next Test

1. Seroconversion is often used as an indicator of infection or immunity.
2. The time it takes for seroconversion to occur can vary depending on the pathogen and individual immune response.
3. In laboratory analysis, seroconversion can be detected through various assays such as ELISA or agglutination tests.
4. It is critical in diagnosing diseases like HIV, where detection of antibodies confirms infection.
5. Understanding the window period before seroconversion occurs is crucial for accurate diagnosis and avoiding false negatives.

Review Questions

Related terms

Agglutination Assay: A test that measures the aggregation of particles, often used to detect antibodies or antigens.

ELISA:

Enzyme-linked immunosorbent assay, a common laboratory technique for detecting and quantifying substances such as proteins, antibodies, and hormones.

Window Period: The time between initial infection and when a test can reliably detect markers of infection.