🦠microbiology review

Secondary immunodeficiency

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Secondary immunodeficiency is an acquired condition resulting from external factors that impair the immune system. It differs from primary immunodeficiency, which is genetic.

5 Must Know Facts For Your Next Test

  1. Secondary immunodeficiency can result from infections such as HIV, malnutrition, or chemotherapy.
  2. Unlike primary immunodeficiencies, secondary types are not inherited but acquired during life.
  3. Patients with secondary immunodeficiency are more susceptible to infections and may require specific treatments to manage their immune function.
  4. Common signs include recurrent infections, slow recovery, and severe illness from common pathogens.
  5. Diagnosis often includes a detailed medical history, physical examination, and various laboratory tests to identify underlying causes.

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