Secondary antibody response

Definition

The secondary antibody response is the immune system's more rapid and robust response to an antigen upon second and subsequent exposures. It is characterized by a higher production of antibodies, especially IgG, due to memory B cells.

5 Must Know Facts For Your Next Test

1. The secondary antibody response is faster and stronger than the primary response due to the presence of memory B cells.
2. IgG is the predominant antibody produced during the secondary response, unlike IgM which dominates the primary response.
3. Memory B cells generated during the initial exposure can persist for years or even a lifetime, providing long-term immunity.
4. The secondary antibody response often requires less antigen to trigger compared to the primary response.
5. Vaccinations aim to induce a strong secondary antibody response upon future exposures to the pathogen.

Review Questions

Related terms

Primary Antibody Response:

The initial immune reaction to an antigen, characterized by slower and lower levels of antibody production.

Memory B Cells:

Long-lived B cells that remember past infections and contribute to a quicker and stronger immune response upon re-exposure.

IgG:

A class of antibodies that play a crucial role in the secondary immune response by neutralizing pathogens more effectively.