Sebum

Definition

Sebum is an oily substance produced by sebaceous glands in the skin. It plays a role in maintaining skin hydration and providing a barrier against microbial invasion.

5 Must Know Facts For Your Next Test

1. Sebum contains lipids, fatty acids, and waxes that contribute to its protective properties.
2. It has antimicrobial activity due to the presence of free fatty acids and other compounds.
3. Overproduction of sebum can lead to acne by clogging hair follicles and providing an environment for bacterial growth.
4. Sebum composition can vary based on factors like age, diet, hormones, and genetics.
5. Normal microbiota on the skin can metabolize components of sebum, influencing both skin health and microbial ecology.

Review Questions

• What are the main components of sebum?
• How does sebum contribute to the skin's chemical defenses?
• What role does sebum play in relation to normal microbiota on the skin?

Related terms

Lipids: Organic compounds that are fatty acids or derivatives, insoluble in water but soluble in organic solvents.

Innate Immunity: The body's first line of defense against pathogens, consisting of physical barriers, chemical barriers, and immune cells.

Sebaceous Glands: Small oil-producing glands present in the skin connected to hair follicles that secrete sebum.