key term - Pyoverdin

Definition

Pyoverdin is a fluorescent siderophore produced by Pseudomonas aeruginosa. It plays a critical role in iron acquisition and virulence.

5 Must Know Facts For Your Next Test

1. Pyoverdin is essential for the survival of Pseudomonas aeruginosa in iron-limited environments such as human tissues.
2. It contributes to the greenish color observed in infections caused by Pseudomonas aeruginosa.
3. Pyoverdin binds to iron with high affinity, facilitating its uptake by bacterial cells.
4. Production of pyoverdin increases under low-iron conditions, enhancing bacterial pathogenicity.
5. Pyoverdin can also serve as a signaling molecule, regulating the expression of other virulence factors.

Review Questions

Related terms

Siderophore: Molecules that bind and transport iron in microorganisms.

Pseudomonas aeruginosa:

A common Gram-negative bacterium that can cause disease in humans.

Virulence Factor: Molecules produced by pathogens that contribute to their ability to cause disease.