Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Pseudomurein is a structural polysaccharide found in the cell walls of some archaea. It is similar to peptidoglycan in bacteria but has different chemical linkages and sugar components.
5 Must Know Facts For Your Next Test
Pseudomurein consists of repeating units of N-acetyltalosaminuronic acid and N-acetylglucosamine.
Unlike peptidoglycan, pseudomurein has β(1→3) glycosidic bonds instead of β(1→4) glycosidic bonds.
Pseudomurein is resistant to lysozyme, an enzyme that breaks down bacterial cell walls containing peptidoglycan.
It provides structural support to archaeal cell walls, particularly in methanogens.
The presence of pseudomurein distinguishes certain archaea from bacteria and other archaea that do not possess it.