Plasma cells

Definition

Plasma cells are differentiated B lymphocytes that produce and secrete large quantities of antibodies. They play a critical role in the humoral immune response by targeting specific antigens.

5 Must Know Facts For Your Next Test

1. Plasma cells originate from activated B cells during an immune response.
2. They have an extensive rough endoplasmic reticulum for antibody production.
3. Each plasma cell produces antibodies specific to one antigen.
4. Plasma cells typically reside in the bone marrow and lymphoid tissues.
5. Their lifespan can vary from a few days to several months depending on the type of immune response.

Review Questions

• What is the primary function of plasma cells in the immune system?
• Where do plasma cells typically reside after differentiation?
• How does a plasma cell's structure support its function?

Related terms

B Lymphocytes:

White blood cells that mature in the bone marrow and are part of the adaptive immune system.

Antibodies:

Proteins produced by plasma cells that specifically bind to antigens to neutralize or mark them for destruction.

Humoral Immunity:

Aspect of immunity mediated by macromolecules found in extracellular fluids such as antibodies, complement proteins, and certain antimicrobial peptides.