Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Phenolic compounds are a class of chemical disinfectants that denature proteins and disrupt cell membranes, leading to microbial death. They are commonly used in healthcare settings for their broad-spectrum antimicrobial activity.
5 Must Know Facts For Your Next Test
Phenolic compounds are effective against a wide range of microorganisms, including bacteria, fungi, and viruses.
They can be used on surfaces, equipment, and skin but may cause irritation with prolonged exposure.
The effectiveness of phenolic compounds can be diminished in the presence of organic material such as blood or pus.
Common examples include triclosan and hexachlorophene, which have been used in antiseptic soaps and surgical scrubs.
Phenolics work by disrupting cell walls and precipitating cellular proteins, making them lethal to microbes.
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Related terms
Disinfectant: A chemical agent used to destroy or inhibit the growth of harmful organisms.