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Orfloxacin

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Microbiology

Definition

Ofloxacin is a broad-spectrum antibiotic belonging to the fluoroquinolone class, used to treat various bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV.

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5 Must Know Facts For Your Next Test

  1. Ofloxacin is effective against both Gram-positive and Gram-negative bacteria.
  2. Common side effects include nausea, diarrhea, and dizziness.
  3. It is often used to treat gastrointestinal infections caused by bacteria like Salmonella and Shigella.
  4. Ofloxacin can lead to the development of antibiotic-resistant bacteria if misused or overused.
  5. The drug should not be taken with antacids containing magnesium or aluminum as they can interfere with its absorption.

Review Questions

  • What types of bacteria is Ofloxacin effective against?
  • What are common side effects of Ofloxacin?
  • Why is it important to avoid taking Ofloxacin with certain antacids?

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