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🦠microbiology review

Naked virus

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

A naked virus is a virus that lacks an outer lipid envelope and consists only of a nucleocapsid. These viruses are typically more resistant to environmental conditions compared to enveloped viruses.

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5 Must Know Facts For Your Next Test

  1. Naked viruses are composed solely of a nucleocapsid, which includes the viral genome and protein coat.
  2. They are generally more stable in harsh environmental conditions such as extreme pH and temperature.
  3. Transmission is often through the fecal-oral route or direct contact with contaminated surfaces.
  4. Examples include poliovirus, adenovirus, and parvovirus.
  5. Naked viruses usually enter host cells through endocytosis.

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