Mucins

Definition

Mucins are high molecular weight glycoproteins produced by epithelial tissues, serving as a protective barrier on mucosal surfaces. They play a crucial role in lubrication, cell signaling, and pathogen defense.

5 Must Know Facts For Your Next Test

1. Mucins are essential for maintaining the moisture and integrity of the skin and eye surfaces.
2. They trap pathogens and prevent their entry into deeper tissues, aiding in immune defense.
3. In the eyes, mucins contribute to the tear film that protects and lubricates the cornea.
4. Dysfunction or altered production of mucins can lead to various infections or inflammatory conditions.
5. Mucins interact with the normal microbiota, helping to maintain a balanced microbial environment.

Review Questions

• What primary functions do mucins serve in epithelial tissues?
• How do mucins contribute to the immune defense mechanisms of the skin and eyes?
• What role do mucins play in maintaining a balanced microbial environment?

Related terms

Glycoprotein: A molecule consisting of a protein and carbohydrate (glycan) component.

Tear Film: A thin layer of fluid covering the eye's surface, composed of water, oils, mucus, and proteins.

Normal Microbiota: The community of microorganisms that reside on or within different parts of an organism without causing disease.