🦠microbiology review

Mononucleosis

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Mononucleosis, often called 'mono' or the 'kissing disease,' is an infectious illness caused by the Epstein-Barr virus (EBV). It primarily spreads through saliva and can cause fever, sore throat, swollen lymph nodes, and fatigue.

5 Must Know Facts For Your Next Test

  1. Mononucleosis is primarily caused by the Epstein-Barr virus (EBV), a member of the herpesvirus family.
  2. Transmission occurs mainly through saliva but can also spread through blood and other bodily fluids.
  3. Common symptoms include fever, sore throat, swollen lymph nodes, and extreme fatigue; these may last for weeks to months.
  4. Diagnosis is typically confirmed via a blood test checking for EBV-specific antibodies or an atypical white blood cell count.
  5. There is no specific antiviral treatment for mono; management focuses on relieving symptoms such as pain and fever.
2,589 studying →