Mode of action

Definition

Mode of action describes the specific biochemical interaction through which an antimicrobial drug produces its effect on a microorganism. It involves targeting specific cellular components or processes to inhibit growth or kill the bacteria.

5 Must Know Facts For Your Next Test

1. Modes of action include inhibition of cell wall synthesis, protein synthesis, nucleic acid synthesis, and metabolic pathways.
2. Beta-lactam antibiotics like penicillin target bacterial cell wall synthesis.
3. Tetracyclines inhibit protein synthesis by binding to the 30S ribosomal subunit.
4. Fluoroquinolones interfere with bacterial DNA replication by inhibiting DNA gyrase and topoisomerase IV.
5. Sulfonamides mimic para-aminobenzoic acid (PABA) and inhibit folic acid synthesis in bacteria.

Review Questions

Related terms

Antibiotic Resistance:

The ability of bacteria to withstand the effects of an antibiotic.

Bacteriostatic:

A type of antimicrobial agent that inhibits the growth or reproduction of bacteria.

Bactericidal:

A type of antimicrobial agent that kills bacteria.