Microbiology

study guides for every class

that actually explain what's on your next test

Maturation

from class:

Microbiology

Definition

Maturation is the process by which viral particles undergo structural changes to become fully infectious. This step often involves proteolytic cleavage and assembly of viral components.

congrats on reading the definition of maturation. now let's actually learn it.

ok, let's learn stuff

5 Must Know Facts For Your Next Test

  1. Maturation typically occurs after the assembly phase in the viral life cycle.
  2. Proteases play a crucial role in the maturation process by cleaving viral polyproteins.
  3. The maturation process ensures that viral particles are structurally competent for infection.
  4. In HIV, maturation involves the cleavage of Gag and Gag-Pol polyproteins by the viral protease.
  5. Inhibition of viral maturation is a target for antiviral drug development.

Review Questions

  • What role do proteases play in viral maturation?
  • At what stage in the viral life cycle does maturation occur?
  • How does inhibiting maturation affect viral infectivity?
© 2024 Fiveable Inc. All rights reserved.
AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.
Glossary
Guides